Location History:
- Kanagawa, JP (2011 - 2022)
- Tokyo, JP (2021 - 2023)
Company Filing History:
10 out of 950 
1 out of 987 
Years Active: 2011-2023
Title: The Innovative Achievements of Takahiro Ishiguro
Introduction
Takahiro Ishiguro is a prominent inventor located in Kanagawa, Japan, known for his significant contributions to the field of genetic engineering. With a portfolio of 10 patents, he has made remarkable strides in developing genetically modified animals that serve as models for medical research and therapeutic evaluation.
Latest Patents
Ishiguro's latest innovations include two noteworthy patents. The first is a gene-modified mouse expressing the human GPC3 polypeptide. This invention pertains to genetically modified non-human animals that lack expression of an endogenous GPC3 polypeptide and express the human variant at a physiologically adequate level. The accompanying methods enhance the production of these animals and facilitate the evaluation of test substances in terms of safety and therapeutic effects on diseases.
The second patent involves a genetically modified non-human animal with a human CD3 gene substituted for endogenous CD3 genes. This invention consists of non-human animals deficient in specific types of CD3 genes, allowing for mature T cell differentiation and the production of immunocompetent cells. This advancement is crucial for the efficient evaluation and screening of therapeutic agents involving human CD3-mediated targeted drugs.
Career Highlights
Throughout his career, Takahiro Ishiguro has made a significant impact in the field of biotechnology. He has held notable positions in esteemed organizations such as Chugai Seiyaku Kabushiki Kaisha and Osaka University. His work has paved the way for advancements in the understanding of genetic therapies and their applications.
Collaborations
Ishiguro has collaborated with talented individuals in the industry, including Tomoyuki Igawa and Yasuko Kinoshita. These collaborations have fostered an environment of innovation and mutual growth, leading to the development of groundbreaking technologies that advance medicine.
Conclusion
Takahiro Ishiguro's inventive spirit and dedication to advancing genetic engineering have firmly established him as a leading inventor in his field. With his latest patents addressing significant gaps in medical research, Ishiguro continues to play a pivotal role in the development of innovative solutions that could transform therapeutic strategies for various diseases. His contributions reflect the importance of inventiveness and collaboration in driving progress in science and technology.