The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2011
Filed:
Jul. 08, 2005
Kiyotaka Nakano, Ibaraki, JP;
Takeshi Yoshino, Ibaraki, JP;
Jun-ichi Nezu, Ibaraki, JP;
Hiroyuki Tsunoda, Ibaraki, JP;
Tomoyuki Igawa, Shizuoka, JP;
Hiroko Konishi, Shizuoka, JP;
Megumi Tanaka, Shizuoka, JO;
Izumi Sugo, Shizuoka, JP;
Shigeto Kawai, Kanagawa, JP;
Takahiro Ishiguro, Kanagawa, JP;
Yasuko Kinoshita, Kanagawa, JP;
Kiyotaka Nakano, Ibaraki, JP;
Takeshi Yoshino, Ibaraki, JP;
Jun-Ichi Nezu, Ibaraki, JP;
Hiroyuki Tsunoda, Ibaraki, JP;
Tomoyuki Igawa, Shizuoka, JP;
Hiroko Konishi, Shizuoka, JP;
Megumi Tanaka, Shizuoka, JO;
Izumi Sugo, Shizuoka, JP;
Shigeto Kawai, Kanagawa, JP;
Takahiro Ishiguro, Kanagawa, JP;
Yasuko Kinoshita, Kanagawa, JP;
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Abstract
An antibody capable of binding to a specific region of glypican 3, as well as a humanized antibody created based on that antibody are disclosed. The anti-GPC3 antibody of the invention has a higher ADCC activity and CDC activity compared with those of a conventional antibody. The antibody of the present invention is useful as a cell growth inhibitor, an anticancer agent and an agent for diagnosis of cancers.