Ibaraki, Japan

Jun-Ichi Nezu

USPTO Granted Patents = 14 


 

Average Co-Inventor Count = 2.3

ph-index = 4

Forward Citations = 84(Granted Patents)


Company Filing History:


Years Active: 2001-2014

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14 patents (USPTO):Explore Patents

Title: Jun-Ichi Nezu: Innovator in Transporter Genes and Fetal Polypeptides

Introduction

Jun-Ichi Nezu is a prominent inventor based in Ibaraki, Japan. He has made significant contributions to the field of biotechnology, particularly in the cloning of novel transporter genes and the isolation of fetal polypeptides. With a total of 14 patents to his name, Nezu's work has implications for drug development and cancer treatment.

Latest Patents

One of Nezu's latest patents involves the cloning of transporter genes OATP-B, C, D, and E. These four novel transporter genes were successfully identified through screening based on the human OATP transporter gene sequence. The transporters play a crucial role in the development of drugs by facilitating the transport of biological substances and various drugs. Additionally, it was discovered that these transporter genes possess single nucleotide polymorphisms (SNPs). Gene diagnosis utilizing these polymorphisms allows for the assessment of drug therapy efficacy. Another significant patent pertains to the isolation of novel fetal polypeptides from human liver. The genes fls353 and fls485 were isolated from human fetal liver-derived cDNAs and are specifically expressed in fetal tissues, which are rich in undifferentiated and actively proliferating cells. High expression levels of these genes were also noted in various cancer cells, indicating their potential as tools for developing tumor treatment drugs.

Career Highlights

Throughout his career, Nezu has worked with notable companies, including Chugai Seiyaku Kabushiki Kaisha. His innovative research has positioned him as a key figure in the biotechnology sector, contributing to advancements in drug development and genetic research.

Collaborations

Nezu has collaborated with several professionals in his field, including Asuka Ose and Asuka Oku, who is a woman. These collaborations have further enriched his research and development efforts.

Conclusion

Jun-Ichi Nezu's contributions to the field of biotechnology, particularly in transporter genes and fetal polypeptides, highlight his innovative spirit and dedication to advancing medical science. His work continues to pave the way for new therapeutic approaches in drug development and cancer treatment.

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