Company Filing History:
12 out of 2,405 
Years Active: 2021-2025
Title: Innovative Contributions of Patrick McHugh in Pneumococcal Vaccination
Introduction
Patrick McHugh, an accomplished inventor based in Pipersville, PA, is recognized for his significant contributions to the field of immunology and vaccine development. With a remarkable portfolio, he holds a total of 10 patents, showcasing his commitment to advancing medical science through innovation.
Latest Patents
Among his latest innovations, McHugh has developed a range of processes designed for the formulation of pneumococcal polysaccharides for conjugation to a carrier protein. His inventions offer several process improvements related to the conjugation of capsular polysaccharides to a carrier protein. These advancements are serotype specific and include methods such as acid hydrolysis and the addition of sodium chloride in the reductive amination reaction, along with the incorporation of sucrose to facilitate the dissolution of polysaccharides.
Another notable patent outlines methods for producing Streptococcus pneumoniae capsular polysaccharide carrier protein conjugates from lyospheres. This innovative method involves separately lyophilizing activated pneumococcal polysaccharides of specific serotypes and carrier proteins into lyospheres, followed by a precise mixing and reconstitution in an organic solvent to generate polysaccharide-carrier protein conjugates. These conjugates can then be utilized to create multivalent pneumococcal immunogenic compositions, enhancing the efficacy of vaccines.
Career Highlights
Patrick McHugh is employed at Merck Sharp & Dohme Corporation, a renowned entity in the pharmaceutical domain. His work focuses on developing cutting-edge solutions that significantly improve vaccine formulation and effectiveness. McHugh's dedication to innovation and research has played a pivotal role in advancing public health initiatives, particularly in the fight against pneumococcal diseases.
Collaborations
Throughout his career, McHugh has collaborated with notable professionals in the field, including Chitrananda Abeygunawardana and Michael Albert Winters. These partnerships reflect his commitment to teamwork and cross-disciplinary innovation, essential for addressing complex challenges in vaccine development.
Conclusion
In summary, Patrick McHugh's inventive contributions to the field of pneumococcal vaccine development underscore his status as a leading innovator. His latest patents not only demonstrate technical prowess but also hold the promise of advancing public health initiatives through improved vaccination strategies. As the landscape of immunology continues to evolve, McHugh's work is likely to remain at the forefront of innovations designed to combat infectious diseases.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.