Lansdale, PA, United States of America

Ju-Tao Guo

USPTO Granted Patents = 10 

 

 

Average Co-Inventor Count = 4.1

ph-index = 3

Forward Citations = 51(Granted Patents)


Company Filing History:


Years Active: 2008-2018

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10 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Inventor Ju-Tao Guo

Introduction

Ju-Tao Guo, an accomplished inventor based in Lansdale, PA, has made significant contributions to the field of medical science, particularly in the management of chronic hepatitis B virus (HBV) infections. With a portfolio of 10 patents, Guo's work focuses on innovative therapeutic approaches aimed at combating the challenges posed by HBV.

Latest Patents

Two of Guo's latest patents showcase his groundbreaking research. The first patent, titled "Modulation of hepatitis B virus cccDNA transcription," presents small molecule inhibitors of HBV covalently closed circular (ccc) DNA. These compounds provide therapeutic options for managing chronic HBV by achieving epigenetic modifications and inhibiting histone deacetylase activity, which ultimately modulates HBV cccDNA transcription.

The second patent, “Use of STING agonists to treat chronic hepatitis B virus infection,” outlines methods for stimulating the innate cytokine response in immune cells using small molecular agonists of STING. This approach aims to suppress HBV replication within hepatocytes, offering new pathways for the treatment of chronic HBV infections. Furthermore, this patent discusses methods for identifying compounds useful in the fight against HBV.

Career Highlights

Ju-Tao Guo's impressive career includes notable affiliations with esteemed institutions such as Drexel University and the Baruch S. Blumberg Institute. His work has contributed significantly to the academic and practical understanding of viral diseases, particularly those relating to hepatitis B.

Collaborations

Throughout his career, Guo has collaborated with distinguished researchers including Timothy Michael Block and Jinhong Chang. These collaborations have played a crucial role in advancing his research and expanding the potential impacts of his inventions in the medical field.

Conclusion

Inventor Ju-Tao Guo stands out as a pioneering figure in the fight against chronic HBV, with a robust portfolio of patents that reflect his commitment to innovation in medicine. His contributions through research and collaboration with other experts underscore the importance of continued exploration and invention in addressing critical health challenges.

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