The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 30, 2025

Filed:

Oct. 01, 2019
Applicant:

Baruch S. Blumberg Institute, Doylestown, PA (US);

Inventors:

Jinhong Chang, Chalfont, PA (US);

Yanming Du, Cheshire, CT (US);

Ju-Tao Guo, Lansdale, PA (US);

Assignee:

BARUCH S. BLUMBERG INSTITUTE, Doylestown, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 317/68 (2006.01); A61P 35/00 (2006.01); C07C 233/66 (2006.01); C07C 235/56 (2006.01); C07D 213/82 (2006.01); C07D 319/18 (2006.01); C07D 321/10 (2006.01); C07D 405/12 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 317/68 (2013.01); A61P 35/00 (2018.01); C07C 233/66 (2013.01); C07C 235/56 (2013.01); C07D 213/82 (2013.01); C07D 319/18 (2013.01); C07D 321/10 (2013.01); C07D 405/12 (2013.01); C07D 417/12 (2013.01); C07C 2602/10 (2017.05);
Abstract

Pharmaceutical compositions of the invention comprise functionalized benzamide derivatives useful as cyclic GMP-AMP synthase-Stimulator of interferon gene (cGAS-STING) pathway agonists, and useful for treating viral diseases and boost antitumor immunity.


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