Company Filing History:
15 out of 24 
10 out of 3,923 
4 out of 95 
Years Active: 2009-2025
Title: **John Louis Diener: Pioneering Innovations in Metabolic Disorder Treatments**
Introduction
John Louis Diener, based in Cambridge, MA, is an esteemed inventor known for his extensive contributions to the field of metabolic disorder treatments. With a remarkable portfolio of 32 patents, his work continues to impact medical research and therapeutic applications significantly.
Latest Patents
Diener’s latest innovations focus on advanced therapeutic methods. One of his notable patents is the "Methods of treating HIV-HAART induced partial lipodystrophy with FGF21 protein variant FC fusion proteins." This invention aims to identify new therapeutic avenues for the FGF21 polypeptide and its variants, addressing a range of metabolic diseases associated with insulin signaling defects, such as type 1 diabetes mellitus, mixed dyslipidemia, and HIV-HAART induced partial lipodystrophy. The patent seeks to reduce morbidity and mortality among critically ill patients suffering from these conditions.
Another significant patent is centered on "3' end caps, 5' end caps and combinations thereof for therapeutic RNA." This disclosure covers nucleic acids with modifications at the ends, leading to improved expression, reduced immunogenicity, and greater stability compared to unmodified nucleic acids. These breakthroughs have valuable implications for RNA-based therapies.
Career Highlights
Diener has amassed an impressive career, having worked with prominent companies in the pharmaceutical industry. He has been associated with Archemix Corporation and Novartis AG, where he has contributed to cutting-edge research and development in biotechnology. His extensive knowledge and expertise have paved the way for significant advancements in therapeutic methods.
Collaborations
Throughout his career, Viener has collaborated with renowned professionals in the field, including Antonin de Fougerolles and Emma Hickman. These collaborations have facilitated the cross-pollination of ideas, enhancing the innovative approaches in treating metabolic disorders.
Conclusion
John Louis Diener stands out as a highly influential inventor whose work has led to transformative developments in the treatment of metabolic diseases. His dedication to research and innovation exemplifies the spirit of progress in medical science, promising brighter futures for patients affected by these complex disorders.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.