The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2025

Filed:

Mar. 30, 2023
Applicant:

Novartis Ag, Basel, CH;

Inventors:

John Louis Diener, Cambridge, MA (US);

Lars Gadtke, Munich, DE;

Felix Hartlepp, Munich, DE;

Tiancen Hu, Woodbridge, CT (US);

Kathrin Ladetzki-Baehs, Planegg, DE;

Michael John Romanowski, Lexington, MA (US);

Cesare Russo, Bachlettenstrasse, CH;

Xenia Wezler, Munich, DE;

Xiaoling Xie, Cambridge, MA (US);

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C12N 15/63 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61P 9/00 (2006.01); A61P 13/12 (2006.01); C07K 14/58 (2006.01); C07K 14/72 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2869 (2013.01); C12N 15/63 (2013.01); A61K 39/3955 (2013.01); A61K 2039/505 (2013.01); A61K 45/06 (2013.01); A61P 9/00 (2018.01); A61P 13/12 (2018.01); C07K 14/58 (2013.01); C07K 14/72 (2013.01); C07K 2317/50 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/75 (2013.01);
Abstract

This disclosure relates to anti-Natriuretic Peptide Receptor 1 (NPR1) antibodies including agonist antibodies which are able to activate the NPR1 receptor, pharmaceutical compositions comprising the same, and methods of treatment comprising the same.


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