The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 03, 2013
Filed:
Sep. 13, 2012
Antonin DE Fougerolles, Cambridge, MA (US);
John Diener, Cambridge, MA (US);
Emma Hickman, Horsham, GB;
Gregory Hinkle, Cambridge, MA (US);
Stuart Milstein, Cambridge, MA (US);
Anne-marie Pulichino, Cambridge, MA (US);
Andrew Griffin Sprague, Cambridge, MA (US);
Antonin De Fougerolles, Cambridge, MA (US);
John Diener, Cambridge, MA (US);
Emma Hickman, Horsham, GB;
Gregory Hinkle, Cambridge, MA (US);
Stuart Milstein, Cambridge, MA (US);
Anne-Marie Pulichino, Cambridge, MA (US);
Andrew Griffin Sprague, Cambridge, MA (US);
Novartis AG, Basel, CH;
Abstract
The present disclosure relates to RNAi agents useful in methods of treating Beta-ENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (PHA1), Liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC.