The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 2016
Filed:
Sep. 16, 2003
Applicants:
Charles Wilson, Concord, MA (US);
David Epstein, Belmont, MA (US);
John L. Diener, Cambridge, MA (US);
Inventors:
Charles Wilson, Concord, MA (US);
David Epstein, Belmont, MA (US);
John L. Diener, Cambridge, MA (US);
Assignee:
ARCHEMIX LLC, San Francisco, CA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/21 (2006.01); C07K 14/16 (2006.01); C12N 15/115 (2010.01); C07K 16/10 (2006.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); C07K 16/1063 (2013.01); C12N 2310/317 (2013.01); C12N 2310/321 (2013.01); C12N 2310/322 (2013.01); C12N 2310/3513 (2013.01);
Abstract
Methods are provided for identifying aptamer regulators. Aptamer regulators are aptamers that bind to a target wherein binding of the aptamer regulator to the target increases the binding affinity of the target for a target partner relative to the affinity of the target for the target partner when the target is not bound by the aptamer regulator such that binding of the aptamer regulator to the target is a prerequisite for target-target partner complex formation.