Gregory Walter Hiller

Title: Gregory Walter Hiller - Innovator in Biotechnological Advancements

Introduction

Gregory Walter Hiller is an accomplished inventor based in Wakefield, Massachusetts, recognized for his contributions in the field of bioprocessing and protein production. With a total of 10 patents to his name, Hiller has significantly advanced the methodologies used in cell culture technology and bioreactor systems.

Latest Patents

Among his latest innovations, Hiller developed a "Linked perfusion to continuous-flow stirred-tank reactor cell culture system." This patent details methods for protein production through a two-step approach involving a culture bioreactor and a production bioreactor. Specifically, the approach entails culturing cells that contain a gene encoding the protein of interest in a continuous perfusion culture bioreactor before inoculating those cells into a continuously stirred tank reactor production bioreactor, allowing for efficient protein production.

Another notable invention is the "Cell-controlled perfusion in continuous culture," which presents methods for continuous perfusion culture by enabling cells to manage the addition rate of perfusion medium to the bioreactor based on pH changes. This innovation enhances the control and efficiency of mammalian cell culture bioreactors, showcasing Hiller's commitment to improving biotechnological processes.

Career Highlights

Hiller's career boasts impressive affiliations with leading organizations in the pharmaceutical and biotechnology industries. He has worked with notable companies such as Boehringer Ingelheim International GmbH and Pfizer Corporation, where he has utilized his expertise to innovate and refine protein production techniques.

Collaborations

Throughout his career, Hiller has collaborated with esteemed colleagues, including Matthew Paul Gagnon and Bhanu Chandra Mulukutla. These partnerships highlight the collaborative nature of innovation within the biotechnological field, emphasizing the importance of teamwork in achieving remarkable advancements.

Conclusion

Gregory Walter Hiller's inventions underline the significant impact of biotechnology on protein production processes. His work not only expands the boundaries of scientific understanding but also brings practical applications that can revolutionize the way bioprocessing is conducted in the industry. As he continues to innovate, Hiller remains a vital figure in the ongoing evolution of biotechnology.