The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2024
Filed:
Apr. 22, 2008
Jose Manuel Gomes, Chelmsford, MA (US);
Yen-tung Luan, Chelmsford, MA (US);
Gregory Walter Hiller, Wakefield, MA (US);
Wenge Wang, North Chelmsford, MA (US);
Jose Manuel Gomes, Chelmsford, MA (US);
Yen-Tung Luan, Chelmsford, MA (US);
Gregory Walter Hiller, Wakefield, MA (US);
Wenge Wang, North Chelmsford, MA (US);
WYETH LLC, Madison, NJ (US);
Abstract
Methods of producing a protein in cell culture comprising an anti-senescence compound, such as the antioxidant carnosine, are provided. According to teachings of the present invention, cells grown in a cell culture medium comprising an anti-senescence compound exhibit increased viability and productivity. Furthermore, cell cultures grown in the presence of an anti-senescence compound exhibit decreased levels of high molecular weight aggregates in the cell culture medium.