Location History:
- Nanjing, CN (2019 - 2022)
- Kunming, CN (2022)
- Jiangsu, CN (2021 - 2023)
Company Filing History:
5 out of 34 
1 out of 57 
1 out of 159 Years Active: 2019-2025
Title: Innovations and Contributions of Inventor Xiaoli Xu
Introduction
Xiaoli Xu is a prominent inventor based in Nanjing, China. He has made significant contributions to the field of pharmaceutical sciences, particularly in the development of innovative compounds for treating leukemia and other related diseases. With a total of seven patents to his name, his work showcases a commitment to advancing medical research and therapeutic options.
Latest Patents
Xiaoli Xu's latest patents include an aniline-based WDR5 protein-protein interaction inhibitor. This inhibitor selectively targets the WDR5 protein and its interacting proteins, such as MLL, to inhibit the proliferation of leukemia cells. The research demonstrates that it can also inhibit the methylation of H3K4 and the expression of downstream Hox/Meis-1 genes at the cellular level. Additionally, he has developed a hydrogen peroxide-responsive KEAP1-NRF2 PPI inhibitor prodrug. This innovative prodrug is designed to achieve targeted activation of Nrf2 and enhance therapeutic efficacy through a novel ROS-responsive mechanism. It represents a significant advancement in the field of oral administration of prodrugs.
Career Highlights
Xiaoli Xu has worked with notable institutions, including China Pharmaceutical University and China Tobacco Yunnan Industrial Co., Ltd. His experience in these organizations has allowed him to collaborate on various research projects and contribute to the development of new therapeutic agents.
Collaborations
Xiaoli Xu has collaborated with esteemed colleagues, including Qidong You and Xiaoke Guo. Their combined expertise has fostered a productive research environment, leading to innovative solutions in the pharmaceutical field.
Conclusion
Xiaoli Xu's contributions to the field of pharmaceutical sciences through his patents and collaborations highlight his role as a leading inventor. His work continues to pave the way for advancements in medical treatments and therapies.