The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 12, 2021
Filed:
Nov. 27, 2015
Jiangsu Hengrui Medicine Co., Ltd., Jiangsu, CN;
Qidong You, Jiangsu, CN;
Xiaojin Zhang, Jiangsu, CN;
Yonghua Lei, Jiangsu, CN;
Tianhan Hu, Jiangsu, CN;
Xingsen Wu, Jiangsu, CN;
Haopeng Sun, Jiangsu, CN;
Xiaoke Guo, Jiangsu, CN;
Xiaoli Xu, Jiangsu, CN;
Jiangsu Hengrui Medicine Co., Ltd., Jiangsu, CN;
Abstract
The present invention relates to the field of pharmaceutical chemistry. In particular, the present invention relates to a class of alkynyl pyridine prolyl hydroxylase inhibitors (I). The experiments show that such a compound has good activity of inhibiting prolyl hydroxylase, and can enhance the generation and secretion of erythropoietin in cell or animal models, and thus can promote the generation of red cells, and can be used for the treatment or prevention of anemia, such as chronic kidney disease anemia, and ischemic diseases, including ischemic strokes, myocardial ischemia and other related diseases. The present invention also discloses a method for preparing such a compound.