Del Mar, CA, United States of America

William D Huse

This inventor holds 60 USPTO granted patents and 4 published patent applications, plus 2 CIPO patents and 4 EPO patents, primarily in Antibody Engineering (CPC class 536 ). Top assignees: Ixsys, Incorporated, Medimmune Limited, Applied Molecular Evolution. Active years: 1992-2012.

USPTO Granted Patents = 60 

% Patents Active = 68.3

 

 

Average Co-Inventor Count = 2.3

ph-index = 23

Forward Citations = 1,839(Granted Patents)

Forward Citations (Not Self Cited) = 1,750(Dec 10, 2025)


Inventors with similar research interests:


Location History:

  • San Diego, CA (US) (1998)
  • Del Mar, CA (US) (1992 - 2012)

Company Filing History:


Years Active: 1992-2012

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Areas of Expertise:
High Potency Antibodies
Recombinant Antibodies
Immunological Repertoire
Cancer Treatments
Antibody Binding Affinity
Humanized Antibodies
Tumor Specific Antibodies
Surface Expression Libraries
Polymers Production
RSV Antibodies
TNF-α Binding Molecules
Heteromeric Receptors
60 patents (USPTO):Explore Patents

Title: Innovations by William D. Huse: A Pioneer in Antibody Research

Introduction

William D. Huse, based in Del Mar, CA, is a prominent inventor with an impressive portfolio of 60 patents. His research primarily focuses on the field of biotechnology, specifically in the development of advanced methods for producing potent antibodies and polymers.

Latest Patents

Huse's most recent patents include a significant advancement titled "Method for Producing Polymers Having a Preselected Activity." This invention details a method for isolating a gene from the immunological gene repertoire that codes for a receptor capable of binding a specified ligand. Furthermore, it encompasses the production of receptors derived from this gene, with an emphasis on catalytic receptors.

Another noteworthy patent is "High Potency Recombinant Antibodies and Method for Producing Them." This invention outlines the creation of high potency antibodies, alongside methods for their production, including immunologically active fragments. These antibodies exhibit high kinetic association rate constants, targeting antigens related to viruses, cancer cells, and various toxins. The patent also discusses strategies for producing neutralizing antibodies and enhancing their potency, providing potential applications in disease prevention and treatment.

Career Highlights

William D. Huse has made significant contributions to the biotechnology sector through his associations with various companies. He has worked with Ixsys, Incorporated, where he likely developed novel technologies that align with his patent portfolio. Additionally, his tenure at MedImmune Limited has contributed to his reputation as an innovator in the field of immunology.

Collaborations

Throughout his career, Huse has collaborated with notable individuals, such as Jeffry Dean Watkins and Herren Wu. These partnerships have helped foster advancements in biotechnological innovations, further enhancing his work's impact in antibody development.

Conclusion

William D. Huse exemplifies the spirit of innovation within the biotechnology industry, bridging advancements in antibody therapy and polymer production. His extensive patent portfolio reflects his dedication to research and development, setting the stage for future breakthroughs that could lead to significant advancements in medical science.

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