The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 22, 2010
Filed:
Sep. 08, 2003
James F. Young, Darnestown, MD (US);
Leslie S. Johnson, Germantown, MD (US);
William D. Huse, Del Mar, CA (US);
Herren Wu, Houston, TX (US);
Jeffry D. Watkins, Encinitis, CA (US);
James F. Young, Darnestown, MD (US);
Leslie S. Johnson, Germantown, MD (US);
William D. Huse, Del Mar, CA (US);
Herren Wu, Houston, TX (US);
Jeffry D. Watkins, Encinitis, CA (US);
MedImmune, LLC, Gaithersburg, MD (US);
Abstract
Ultra high affinity antibodies with binding affinities in the range of 10M, and even 10Mare disclosed. Such antibodies include antibodies having novel high affinity complementarity determining regions (CDRs), especially those with framework and constant regions derived from either humans or mice. Methods of preparing and screening such antibodies, as well as methods of using them to prevent and/or treat disease, especially virus-induced diseases, are also disclosed.