The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 2010
Filed:
Mar. 01, 2001
James F. Young, Darnestown, MD (US);
Leslie S. Johnson, Germantown, MD (US);
William D. Huse, Del Mar, CA (US);
Herron Wu, Houston, TX (US);
Jeffrey D. Watkins, Encinitis, CA (US);
James F. Young, Darnestown, MD (US);
Leslie S. Johnson, Germantown, MD (US);
William D. Huse, Del Mar, CA (US);
Herron Wu, Houston, TX (US);
Jeffrey D. Watkins, Encinitis, CA (US);
MedImmune, LLC, Gaithersburg, MD (US);
Abstract
High potency antibodies, including immunologically active fragments thereof, having high kinetic association rate constants and optional high affinities are disclosed, along with methods for producing such antibodies. The high potency antibodies disclosed herein are of either the neutralizing or non-neutralizing type and have specificity for antigens displayed by microorganisms, especially viruses, as well as antigenic sites present on cancer cells and on various types of toxins, and the products of toxins. Processes for producing high potency neutralizing antibodies and increasing the potency of already existing neutralizing antibodies are also described. Methods of using said antibodies in the prevention and/or treatment of diseases, especially diseases induced or caused by viruses, are disclosed.