Location History:
- Kumamoto-ken, JP (2006 - 2008)
- Kikuchi-gun, JP (2008 - 2009)
- Kikuchi, JP (2010 - 2020)
- Kumamoto, JP (2007 - 2021)
Company Filing History:
12 out of 114 
4 out of 24 
3 out of 416 
Years Active: 2006-2021
Title: Innovator Spotlight: Toshihiro Nakashima of Kikuchi, Japan
Introduction: Toshihiro Nakashima, based in Kikuchi, Japan, is a prominent inventor known for his significant contributions to the field of biotechnology. With an impressive portfolio of 20 patents, Nakashima has spearheaded innovations that focus on human antibodies, particularly in the context of transthyretin (TTR) related therapies.
Latest Patents: Among Nakashima's latest patents are two groundbreaking human antibodies designed to combat transthyretin-related conditions. The first is an Anti-transthyretin human antibody, which features a complementarity determining region of an H chain and an L chain, as specified in the amino acid sequences shown in SEQ ID NOs: 1 to 6. This human antibody is notable for its ability to specifically bind to transthyretin with a structural change, effectively inhibiting the fibrillization of TTR, making it suitable for therapeutic applications in humans.
The second patent is for an Anti-transthyretin humanized antibody, similarly structured to the first, and it has the same functionality. This humanized antibody also targets TTR and possesses the capability to prevent fibrillization, representing a significant advancement in TTR-targeted therapies.
Career Highlights: Nakashima has played a crucial role in the development of biopharmaceuticals, working with esteemed organizations such as the Juridical Foundation the Chemo-Serotherapeutic Research Institute and Km Biologics Co., Ltd. His research and patents reflect a dedication to addressing pressing health concerns through innovative treatments.
Collaborations: Throughout his career, Nakashima has collaborated with notable colleagues, including Masaharu Torikai and Kazuhisa Sugimura. These partnerships have allowed for a rich exchange of ideas and fostered advancements in biotechnology.
Conclusion: Toshihiro Nakashima's commitment to innovation in the field of antibodies and his impressive patent portfolio underscore his status as a leading inventor. His work has the potential to make a significant impact on medical science, particularly in the treatment of transthyretin-related diseases. As further developments arise from his research, the biopharmaceutical community looks forward to the advancements that Nakashima and his collaborators will continue to contribute.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.