The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 24, 2011
Filed:
Dec. 22, 2009
Toshihiro Nakashima, Kikuchi, JP;
Takumi Sasaki, Kikuchi, JP;
Tsukasa Nishihara, Kikuchi, JP;
Sumiyo Takemoto, Kikuchi, JP;
Atsuko Sakata, Kumamoto, JP;
Masao Ohkuchi, Tokorozawa, JP;
Tomoyuki Koshi, Shiki, JP;
Toshiyuki Edano, Kawagoe, JP;
Toshihiro Nakashima, Kikuchi, JP;
Takumi Sasaki, Kikuchi, JP;
Tsukasa Nishihara, Kikuchi, JP;
Sumiyo Takemoto, Kikuchi, JP;
Atsuko Sakata, Kumamoto, JP;
Masao Ohkuchi, Tokorozawa, JP;
Tomoyuki Koshi, Shiki, JP;
Toshiyuki Edano, Kawagoe, JP;
Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute, Kumamoto-shi, JP;
Kowa Company, Ltd., Nagoya-shi, JP;
Abstract
A modified Staphylococcal enterotoxin B (SEB) having resistance to a protease and a reduced toxicity and a vaccine comprising said modified SEB are provided. A modified SEB which has an amino acid sequence as set forth in SEQ ID NO: 1 wherein each of the lysine at 97-position and the lysine at 98-position are substituted with any other amino acid, or a derivative thereof and a vaccine comprising said modified SEB or a derivative thereof.