The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2014
Filed:
Dec. 26, 2008
Masaharu Torikai, Kumamoto, JP;
Daisuke Ishikawa, Kumamoto, JP;
Toshihiro Nakashima, Kumamoto, JP;
Hirofumi Higuchi, Kumamoto, JP;
Fumihiko Sakai, Tokyo, JP;
Nobuchika Yamamoto, Tokyo, JP;
Hirotada Fujita, Tokyo, JP;
Katsunari Taguchi, Tokyo, JP;
Masaharu Torikai, Kumamoto, JP;
Daisuke Ishikawa, Kumamoto, JP;
Toshihiro Nakashima, Kumamoto, JP;
Hirofumi Higuchi, Kumamoto, JP;
Fumihiko Sakai, Tokyo, JP;
Nobuchika Yamamoto, Tokyo, JP;
Hirotada Fujita, Tokyo, JP;
Katsunari Taguchi, Tokyo, JP;
Juridical Foundation The Chemo-Sero-Therapeutic Research Institute, Kumamoto-shi, JP;
Abstract
The present invention provides a human anti-α9 integrin antibody or an antibody fragment which specifically recognize human α9 integrin and mouse α9 integrin, inhibit interaction with their ligands, particularly, the antibody or antibody fragment which recognize loop regions of human and mouse α9 integrins, a gene encoding the antibody or antibody fragment, a recombinant expression vector containing the gene, a transformant harboring the gene, production method of human anti-α9 integrin antibody or antibody fragment using the transformant, and an agent for the prophylaxis or treatment of rheumatoid arthritis which contains the antibody or antibody fragment.