Location History:
- Palo Alto, CA (US) (2010)
- Pittsburgh, PA (US) (2015 - 2024)
Company Filing History:
5 out of 5 
5 out of 1,860 
3 out of 5,303 
Years Active: 2010-2025
Title: Innovations of Stephen Howard Thorne: A Pioneer in Oncolytic Virus Research
Introduction: Stephen Howard Thorne, an inventive force based in Pittsburgh, PA, holds an impressive portfolio of 14 patents. His groundbreaking work primarily focuses on oncolytic virus technology, which has potential applications in cancer treatment. Through his innovative spirit and research, he has contributed significantly to the field of medical biotechnology.
Latest Patents: Among Stephen Thorne's notable inventions are two significant patents that reflect his dedication to advancing cancer therapies. The first is the "Platform oncolytic vector for systemic delivery," which describes a modified oncolytic virus containing variations in its viral genome and external nucleic acids coding for specific proteins. This innovation seeks to provide a platform for systemic delivery of therapeutic agents. The second patent, "Oncolytic viruses targeting STAT3," relates to modified vaccinia viruses designed to express nucleic acids that influence STAT3 activity. This invention leverages the interaction of PIAS3—an element that mitigates STAT3 activity—to enhance the anti-cancer effectiveness of the vaccinia virus.
Career Highlights: Stephen Thorne has had a prolific career with significant contributions to both academia and the biotech industry. He has worked with the University of Pittsburgh, a renowned institution for medical research, and Kalivir Immunotherapeutics, Inc., where he has played a crucial role in developing innovative cancer treatments through oncolytic virus technology.
Collaborations: Collaboration has been a hallmark of Thorne's career. He has worked alongside esteemed colleagues such as Daniel J Byrd and Mingrui Zhang. Together, they have combined their expertise to push the boundaries of cancer research and therapy.
Conclusion: Stephen Howard Thorne's contributions to oncolytic virus research highlight his role as an innovator in the biotechnological landscape. With 14 patents under his name, his work continues to pave the way for novel cancer treatments, inspiring future innovations in the field. Through his relentless pursuit of knowledge and collaboration with fellow researchers, he stands as a testament to the power of innovation in addressing significant medical challenges.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.