The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 26, 2024

Filed:

Mar. 24, 2017
Applicant:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

Song Li, Wexford, PA (US);

Stephen Howard Thorne, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/76 (2015.01); A61K 9/127 (2006.01); A61K 47/10 (2017.01); A61K 47/24 (2006.01); A61K 47/28 (2006.01); A61K 47/34 (2017.01); A61K 47/69 (2017.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/76 (2013.01); A61K 9/1271 (2013.01); A61K 47/10 (2013.01); A61K 47/24 (2013.01); A61K 47/28 (2013.01); A61K 47/34 (2013.01); A61K 47/6911 (2017.08); A61P 35/00 (2018.01);
Abstract

A method of modifying a virus for in vivo delivery to a region of interest includes forming an enveloping composition including a lipid conjugate formed by conjugating at least one lipid with at least one hydrophilic compound via a linkage which is cleavable under conditions present in the region of interest and combining the virus with the enveloping composition to encompass the virus within the enveloping structure.


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