Oxford, United Kingdom

Peter John Ratcliffe

USPTO Granted Patents = 15 

 

Average Co-Inventor Count = 3.5

ph-index = 3

Forward Citations = 47(Granted Patents)


Location History:

  • Kidlington, GB (1999 - 2001)
  • Oxford, GB (2004 - 2017)

Company Filing History:


Years Active: 1999-2017

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15 patents (USPTO):Explore Patents

Title: The Innovations of Peter John Ratcliffe

Introduction

Peter John Ratcliffe is a prominent inventor based in Oxford, GB. He has made significant contributions to the field of biochemistry, particularly in the area of hydroxylases. With a total of 15 patents to his name, Ratcliffe's work has had a profound impact on medical research and treatment methodologies.

Latest Patents

Among his latest patents is an innovative antibody against human HIF hydroxylase. This novel class of hydroxylases is described as having specific amino acid sequences and variants that exhibit HIF hydroxylation activity. The polypeptides developed in this invention demonstrate prolyl hydroxylase activity, which is crucial for monitoring the interaction of HIF hydroxylase with its substrates. Additionally, modulators of HIF hydroxylase are provided for potential use in treating conditions associated with altered HIF levels or activity. Another significant patent involves an assay for histidinyl hydroxylase activity, which focuses on monitoring the activities of Mina53 and NO66. This invention enables the introduction of S-3-hydroxyhistidinyl residues into peptides and proteins, further advancing the field of biochemistry.

Career Highlights

Throughout his career, Ratcliffe has worked with notable companies such as Isis Innovation Limited and Oxford Biomedica Limited. His expertise and innovative approach have positioned him as a leader in his field, contributing to advancements in medical research and therapeutic applications.

Collaborations

Ratcliffe has collaborated with esteemed colleagues, including Christopher William Pugh and Christopher Joseph Schofield. These partnerships have fostered a collaborative environment that enhances the development of groundbreaking technologies and methodologies.

Conclusion

Peter John Ratcliffe's contributions to the field of biochemistry through his patents and collaborations highlight his role as a significant inventor. His work continues to influence medical research and treatment options, showcasing the importance of innovation in science.

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