The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 05, 2016

Filed:

Feb. 10, 2012
Applicants:

Christopher Joseph Schofield, Oxford, GB;

Alexander Wolf, Oxford, GB;

Wei GE, Oxford, GB;

Armin Thalhammer, Oxford, GB;

Christoph Loenarz, Oxford, GB;

Peter John Ratcliffe, Oxford, GB;

Matthew Edward Cockman, Oxford, GB;

Inventors:

Christopher Joseph Schofield, Oxford, GB;

Alexander Wolf, Oxford, GB;

Wei Ge, Oxford, GB;

Armin Thalhammer, Oxford, GB;

Christoph Loenarz, Oxford, GB;

Peter John Ratcliffe, Oxford, GB;

Matthew Edward Cockman, Oxford, GB;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/26 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/26 (2013.01); G01N 2333/90245 (2013.01);
Abstract

The present invention relates to assays for monitoring activity of OGFOD1 activity, in particular, to assays for identifying modulators of OGFOD1 activity. The invention also relates to assays to monitor the prolyl hydroxylase activity of OGFOD1 on its substrate, the human ribosomal protein RPS23. The invention also enables the introduction of 3-hydroxyprolyl residues into peptides and proteins.


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