The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2016
Filed:
Jul. 25, 2012
Christopher Joseph Schofield, Oxford, GB;
Wei GE, Oxford, GB;
Matthew Edward Cockman, Oxford, GB;
Peter John Ratcliffe, Oxford, GB;
Mathew Louis Coleman, Oxford, GB;
Christopher Joseph Schofield, Oxford, GB;
Wei Ge, Oxford, GB;
Matthew Edward Cockman, Oxford, GB;
Peter John Ratcliffe, Oxford, GB;
Mathew Louis Coleman, Oxford, GB;
Isis Innovation Limited, Oxford, GB;
Abstract
The present invention relates to assays for monitoring activity of Mina53 and NO66 activities, in particular, to assays for identifying modulators of Mina53 and NO66 activities. The invention also relates to assays to monitor the histidinyl hydroxylase activity of Mina53 and NO66 on their substrates, the human ribosomal protein Rpl27a and Rpl8 respectively. The invention also enables the introduction of S-3-hydroxyhistidinyl residues into peptides and proteins.