Location History:
- Lichtervelde, BE (2004 - 2014)
- Nevele, BE (2014 - 2022)
Company Filing History:
12 out of 489 
11 out of 223 
5 out of 366 
Years Active: 2004-2022
Title: Innovations by Nico L M Callewaert: A Pioneer in Membrane Protein Engineering
Introduction
Nico L M Callewaert is a prominent inventor based in Lichtervelde, Belgium, renowned for his significant contributions to the field of membrane protein engineering. With a remarkable portfolio of 15 patents, Callewaert has established himself as a key figure in biotechnology and medical research.
Latest Patents
Callewaert's latest innovations include two notable patents that showcase his expertise. The first patent, titled "Tools and methods for expression of membrane proteins," discloses cells or cellular systems capable of expressing both a membrane protein and a binding domain directed to that protein. This methodology enhances the production of membrane proteins, which are vital for various applications including structural characterization, functional studies, and drug discovery efforts.
The second patent, "Cells producing Fc containing molecules having altered glycosylation patterns and methods and use thereof," focuses on the field of glyco-engineering. This invention demonstrates that Fc-containing molecules, like antibodies, with specific glycosylation patterns exhibit a longer circulating half-life in vivo. This characteristic not only improves patient outcomes by reducing the administration frequency but also maintains therapeutic efficacy, thereby offering significant implications for medical treatments.
Career Highlights
Throughout his career, Callewaert has contributed to esteemed organizations, including Ghent University and VIB VZW. His affiliations with these institutions have enabled him to collaborate on advanced research projects, pushing the boundaries of biotechnology and innovation.
Collaborations
Callewaert has worked alongside esteemed colleagues such as Roland Henri Contreras and Steven C J Geysens. Their collaborative efforts have facilitated groundbreaking advancements in the understanding and application of membrane proteins and glyco-engineering methodologies.
Conclusion
Nico L M Callewaert is a luminary in the field of biotechnology, driven by a passion for innovation and a commitment to advancing scientific knowledge. His patents reflect a deep understanding of membrane proteins, paving the way for new therapeutic strategies and enhancing the potential for drug development. As research continues to evolve, Callewaert’s contributions will likely leave a lasting impact in the realms of medicine and biological engineering.