The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 09, 2021
Filed:
May. 03, 2017
Applicants:
Vib Vzw, Ghent, BE;
Universiteit Gent, Ghent, BE;
Inventors:
Nico L. M. Callewaert, Nevele, BE;
Bram Laukens, Ghent, BE;
Assignees:
VIB VZW, Ghent, BE;
Universiteit Gent, Ghent, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/52 (2006.01); C12P 1/02 (2006.01); C12P 21/00 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
C12P 1/02 (2013.01); A61K 38/1741 (2013.01); C12P 21/00 (2013.01); C12P 21/005 (2013.01); C12Y 302/01096 (2013.01);
Abstract
The present application relates to the field of glyco-engineering, more specifically to glycosylation-engineered fungal cells, more specifically glycosylation-engineered yeast cells, optimized to produce highly homogenous forms of complex N-glycans on recombinant proteins. The invention specifically relates to methods to obtain pharmaceutical compositions comprising recombinant glycoproteins which have homogenous forms of complex N-glycans. In addition, the invention relates to novel pharmaceutical compositions which result from the methods of the invention.