Neil Fred Langille

Title: Neil Fred Langille: Innovator in Pharmaceutical Chemistry

Introduction

Neil Fred Langille is a prominent inventor based in Sudbury, MA (US). He has made significant contributions to the field of pharmaceutical chemistry, holding a total of 6 patents. His work primarily focuses on the synthesis of various pharmaceutical compounds, showcasing his expertise and innovative approach.

Latest Patents

Langille's latest patents include groundbreaking processes for synthesizing Mcl-1 inhibitors and intermediates. One notable patent details the synthesis of sulfonamide intermediates, specifically processes for creating compound Z, which can be utilized in the preparation of Mcl-1 inhibitors. Another significant patent outlines the process for synthesizing apremilast, involving the reaction of 3-acetamidophthalic anhydride with (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine or its salt. This patent also describes methods for isolating apremilast from the reaction mixture.

Career Highlights

Throughout his career, Langille has worked with notable companies in the pharmaceutical industry, including Amgen Inc. and Cytokinetics, Inc. His experience in these organizations has allowed him to develop and refine his innovative techniques in drug synthesis.

Collaborations

Langille has collaborated with esteemed colleagues such as Sheng Cui and Henry Morrison. These partnerships have contributed to the advancement of his research and the successful development of his patented processes.

Conclusion

Neil Fred Langille's contributions to pharmaceutical chemistry through his innovative patents and collaborations highlight his role as a key inventor in the field. His work continues to impact the development of important pharmaceutical compounds.