The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 08, 2025
Filed:
Apr. 25, 2022
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventors:
Matthew G. Beaver, Natick, MA (US);
Carolyn Cohen, Somerville, MA (US);
Neil Fred Langille, Thousand Oaks, CA (US);
Simone Spada, Thousand Oaks, CA (US);
Assignee:
AMGEN INC., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 209/48 (2006.01);
U.S. Cl.
CPC ...
C07D 209/48 (2013.01); C07B 2200/13 (2013.01);
Abstract
Provided herein are processes for synthesizing apremilast comprising reacting 3-acetamidophthalic anhydride and (S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine or a salt thereof to form apremilast. Also provided are processes for isolating apremilast from the reaction mixture, as described herein.