The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 17, 2026

Filed:

Sep. 01, 2021
Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Matthew G. Beaver, Natick, MA (US);

Joseph Michael Dennis, San Diego, CA (US);

Peter Dornan, Stoneham, MA (US);

Steven Mennen, Boston, MA (US);

Jason S. Tedrow, Salem, MA (US);

Neil F. Langille, Sudbury, MA (US);

Carolyn Michelle Cohen, Somerville, MA (US);

Andreas Rene Rotheli, Wellesley, MA (US);

Assignee:

AMGEN INC., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 513/00 (2006.01); C07D 513/10 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 513/10 (2013.01); C07D 519/00 (2013.01); C07B 2200/07 (2013.01);
Abstract

Provided herein are processes for synthesizing Mcl-1 inhibitors and intermediates such as compound Y that can be used to prepare them where the variable Ris as defined herein. In particular, provided herein are processes for synthesizing compound A1, and salts or solvates thereof, compound A2, and salts and solvates thereof, and compound A3 and salts and solvates thereof.


Find Patent Forward Citations

Beaver, Matthew. (2026). Diol desymmetrization by nucleophilic aromatic substitution (U.S. Patent No. 12552808). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12552808

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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