This inventor holds 12 USPTO granted patents and 16 published patent applications and 4 EPO patents. Top assignees: Shanghaitech University, Shanghai Synergy Pharmaceutical Sciences Co., Ltd., Shanghai Synergy Pharmaceutical Sciences, Ltd.. Active years: 2013-2026.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Shanghai, CN (2013 - 2024)
- Suzhou, CN (2024)
Company Filing History:
4 out of 88 
2 out of 7 
2 out of 3 
Years Active: 2013-2026
Title: Innovations in Base Editing: The Patents of Jia Chen
Introduction: Jia Chen, an innovative inventor based in Shanghai, China, holds a remarkable portfolio of seven patents. His research primarily focuses on the groundbreaking field of base editing, an area of genetic engineering that allows for precise modifications in DNA sequences.
Latest Patents: Among his latest contributions to the field are two significant patents. The first is titled "Fusion proteins for improved precision in base editing," which introduces base editors containing a cytidine and a catalytically inactive version of Lachnospiraceae bacterium Cpf1 (LbCpf1). These new base editors demonstrate significantly improved editing efficiency and fidelity compared to traditional Cas9-based editors, featuring unique editing windows. The second patent, "Fusion proteins for base editing," outlines fusion proteins that incorporate an apolipoprotein B mRNA editing enzyme catalytic subunit 3A (APOBEC3A) along with a CRISPR-associated (Cas) protein, and optionally includes a uracil glycosylase inhibitor (UGI). This innovative fusion protein can edit DNA by deaminating cytosine to uracil, even when cytosine is part of a GpC context or is methylated.
Career Highlights: Jia Chen’s career has been marked by his association with reputable institutions and companies. Notably, he has contributed to research and development at ShanghaiTech University and Analog Devices, Inc., where his work has fostered advancements in genetic engineering and biotechnology.
Collaborations: Collaboration has been a key aspect of Jia Chen's success. He has worked alongside esteemed colleagues such as Li Yang and Xingxu Huang, leveraging their expertise to enhance his contributions to the field of base editing.
Conclusion: With a strong foundation in research and a focus on innovation, Jia Chen continues to push the boundaries of genetic engineering. His patents not only represent significant advancements in base editing technology but also pave the way for future developments in the realm of genetic modification and biotechnology.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile