The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2025
Filed:
Aug. 28, 2018
Applicant:
Shanghaitech University, Shanghai, CN;
Inventors:
Jia Chen, Shanghai, CN;
Xingxu Huang, Shanghai, CN;
Li Yang, Shanghai, CN;
Bei Yang, Shanghai, CN;
Xiaosa Li, Shanghai, CN;
Ying Wang, Shanghai, CN;
Yajing Liu, Shanghai, CN;
Assignee:
ShanghaiTech University, Shanghai, CN;
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C07K 14/32 (2006.01); C12N 9/78 (2006.01); C12N 15/10 (2006.01); C12N 15/79 (2006.01);
U.S. Cl.
CPC ...
C12N 15/79 (2013.01); C07K 14/32 (2013.01); C12N 9/22 (2013.01); C12N 9/78 (2013.01); C12N 15/102 (2013.01); C07K 2319/09 (2013.01); C12Y 305/04005 (2013.01);
Abstract
Provided are base editors containing a cytidine and a catalytically inactive version of Lachnospiraceae bacterium Cpf1 (LbCpf1). The new base editors have greatly improved editing efficiency and fidelity as compared to Cas9-based base editors, and have different editing windows.