Company Filing History:
Years Active: 2022-2025
Title: Innovator in Base Editing - Xingxu Huang
Introduction
Xingxu Huang is a renowned inventor based in Shanghai, China, who has made significant contributions to the field of biotechnology. With a total of six patents to his name, Huang is at the forefront of innovations that enhance precision in genetic editing. His work primarily revolves around the development of novel base editing tools that promise to revolutionize the industry.
Latest Patents
Among his latest patents, Huang has developed groundbreaking fusion proteins designed for improved precision in base editing. One notable patent involves base editors containing a cytidine and a catalytically inactive version of Lachnospiraceae bacterium Cpf1 (LbCpf1). These new base editors exhibit greatly improved editing efficiency and fidelity compared to traditional Cas9-based base editors, along with different editing windows.
Another significant patent is centered around a fusion protein comprising a first nCas9 fragment, a chimeric insertion fragment, a second nCas9 fragment, and two UGI fragments. The chimeric insertion fragment is selected from either the APOBEC1 fragment or the APOBEC3A fragment, facilitating cytosine deamination at the target site. This innovative base editing tool reduces off-target effects on both DNA and RNA, while maintaining high specificity and showcasing promising industrialization prospects.
Career Highlights
Xingxu Huang works at ShanghaiTech University, where he continues to advance the field of genetic editing through his research and inventions. His career is marked by a dedication to improving the precision and applications of base editing techniques, making a significant impact in biotechnology.
Collaborations
Throughout his career, Huang has collaborated with talented colleagues such as Jia Chen and Li Yang. These partnerships have not only enriched his work but have also contributed to the overarching goal of enhancing genetic editing technologies.
Conclusion
Xingxu Huang's innovative contributions to the field of biotechnology, especially in base editing, mark him as a leading inventor in his area. With six patents under his belt and ongoing collaborations, Huang is undoubtedly on a path to further revolutionize genetic editing and its applications across various industries.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.