Shanghai, China

Li Yang

USPTO Granted Patents = 37 

 

 

Average Co-Inventor Count = 4.1

ph-index = 5

Forward Citations = 135(Granted Patents)


Location History:

  • Chengdu, CN (2011)
  • Beijing, CN (2013)
  • London, GB (2021)
  • Reading, GB (2021)
  • Shanghai, CN (2015 - 2024)

Company Filing History:


Years Active: 2011-2025

where 'Filed Patents' based on already Granted Patents

37 patents (USPTO):

Title: Innovations of Li Yang: Pioneering Base Editing Technologies

Introduction

Li Yang, based in Shanghai, China, is a prominent inventor known for his contributions to genetic editing technologies. With an impressive portfolio of 33 patents, he has been at the forefront of innovations that enhance precision in base editing techniques.

Latest Patents

Among his recent patents are groundbreaking advancements in the realm of base editing. One of his notable inventions is a set of fusion proteins designed for improved precision in base editing. These base editors incorporate a cytidine and a catalytically inactive version of Lachnospiraceae bacterium Cpf1 (LbCpf1), achieving significantly improved editing efficiency and fidelity compared to traditional Cas9-based editors. Additionally, he has developed fusion proteins that consist of an apolipoprotein B mRNA editing enzyme catalytic subunit 3A (APOBEC3A) and a clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas) protein, which can efficiently modify cytosines to uracils, even under challenging contexts like methylated sites.

Career Highlights

Li Yang has built a distinguished career, having worked with leading organizations such as Huawei Technologies Co., Limited and Shanghaitech University. His work in these entities has played a crucial role in advancing the field of genetics and biotechnology.

Collaborations

Throughout his career, Li Yang has collaborated with talented individuals, including his coworkers Hongzhuo Zhang and Tianle Deng. These partnerships have contributed to the successful development and implementation of innovative technologies in base editing.

Conclusion

Li Yang's extensive patent portfolio and his dedication to improving editing techniques make him a significant figure in the scientific community. His innovations not only advance the field of genetics but also pave the way for future breakthroughs in medical and agricultural applications.

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