Location History:
- Chengdu, CN (2011)
- Beijing, CN (2013)
- London, GB (2021)
- Reading, GB (2021)
- Shanghai, CN (2015 - 2024)
Company Filing History:
Years Active: 2011-2025
Title: Innovations of Li Yang: Pioneering Base Editing Technologies
Introduction
Li Yang, based in Shanghai, China, is a prominent inventor known for his contributions to genetic editing technologies. With an impressive portfolio of 33 patents, he has been at the forefront of innovations that enhance precision in base editing techniques.
Latest Patents
Among his recent patents are groundbreaking advancements in the realm of base editing. One of his notable inventions is a set of fusion proteins designed for improved precision in base editing. These base editors incorporate a cytidine and a catalytically inactive version of Lachnospiraceae bacterium Cpf1 (LbCpf1), achieving significantly improved editing efficiency and fidelity compared to traditional Cas9-based editors. Additionally, he has developed fusion proteins that consist of an apolipoprotein B mRNA editing enzyme catalytic subunit 3A (APOBEC3A) and a clustered regularly interspaced short palindromic repeats (CRISPR)-associated (Cas) protein, which can efficiently modify cytosines to uracils, even under challenging contexts like methylated sites.
Career Highlights
Li Yang has built a distinguished career, having worked with leading organizations such as Huawei Technologies Co., Limited and Shanghaitech University. His work in these entities has played a crucial role in advancing the field of genetics and biotechnology.
Collaborations
Throughout his career, Li Yang has collaborated with talented individuals, including his coworkers Hongzhuo Zhang and Tianle Deng. These partnerships have contributed to the successful development and implementation of innovative technologies in base editing.
Conclusion
Li Yang's extensive patent portfolio and his dedication to improving editing techniques make him a significant figure in the scientific community. His innovations not only advance the field of genetics but also pave the way for future breakthroughs in medical and agricultural applications.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.