Shanghai, China

Bei Yang

USPTO Granted Patents = 4 

Average Co-Inventor Count = 5.6

ph-index = 1

Forward Citations = 1(Granted Patents)


Company Filing History:


Years Active: 2022-2025

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4 patents (USPTO):

Title: Innovations of Inventor Bei Yang: Advancements in Base Editing Technologies

Introduction: Bei Yang, a prominent inventor based in Shanghai, China, has made significant strides in the field of genetic editing. With a total of four patents to his name, Yang's work is paving the way for more precise and efficient methods of base editing, a crucial area in biotechnology and genetics.

Latest Patents: Among his latest innovations are two notable patents. The first patent focuses on "Fusion proteins for improved precision in base editing." This invention includes base editors containing a cytidine and a catalytically inactive version of Lachnospiraceae bacterium Cpf1 (LbCpf1). The newly developed base editors demonstrate a marked increase in editing efficiency and fidelity when compared to conventional Cas9-based base editors and come with varying editing windows. The second patent involves "Fusion proteins for base editing," which encompasses a fusion of an apolipoprotein B mRNA editing enzyme catalytic subunit 3A (APOBEC3A) and a CRISPR-associated (Cas) protein, potentially enhanced by uracil glycosylase inhibitor (UGI). This innovative fusion protein effectively deaminates cytosine to uracil in DNA, even within challenging contexts such as GpC or when methylated.

Career Highlights: Currently, Bei Yang is contributing his expertise at ShanghaiTech University. His academic background and collaborative spirit significantly enhance the research environment, allowing for groundbreaking developments in the field of genetic engineering.

Collaborations: Bei Yang is fortunate to work alongside esteemed colleagues such as Jia Chen and Li Yang. Their combined efforts foster a highly collaborative atmosphere that accelerates innovation and problem-solving, crucial for propelling their research forward.

Conclusion: With a strong focus on precision in base editing technologies, inventor Bei Yang is undoubtedly making profound contributions to the scientific and medical communities. His patents represent significant advancements that have the potential to change the landscape of genetic editing, paving the way for improved treatments and therapies in the near future.

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