Piscataway, NJ, United States of America

Jason Eugene Imbriglio

USPTO Granted Patents = 7 


 

Average Co-Inventor Count = 9.1

ph-index = 1

Forward Citations = 32(Granted Patents)


Company Filing History:


Years Active: 2013-2025

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7 patents (USPTO):

Title: Jason Eugene Imbriglio: Innovator in Cardiometabolic Treatments

Introduction

Jason Eugene Imbriglio is a notable inventor based in Piscataway, NJ (US). He has made significant contributions to the field of pharmaceuticals, particularly in the treatment of cardiometabolic diseases. With a total of seven patents to his name, Imbriglio's work focuses on innovative compounds that address critical health issues.

Latest Patents

Among his latest patents is a groundbreaking invention related to natriuretic peptide receptor A agonists. This invention is useful for the treatment of cardiometabolic diseases, kidney disease, and diabetes. The patent details compounds of Formula I and their pharmaceutically acceptable salts or prodrugs. It also encompasses compositions that include at least one compound of Formula I, along with methods for treating conditions such as high blood pressure, heart failure, kidney disease, and diabetes.

Another significant patent involves substituted 1-methyl-1,2,3,4-tetrahydroisoquinoline molecules as PCSK9 allosteric binders. This invention relates to PCSK9 allosteric binding compounds of Formula I and their pharmaceutically acceptable salts. The patent outlines methods for inducing PCSK9 protein degradation and treating various cardiovascular diseases, including atherosclerosis and hypercholesterolemia.

Career Highlights

Imbriglio has worked with prominent companies in the pharmaceutical industry, including Merck Sharp & Dohme Corporation and Merck Sharpe & Dohme Corp. His experience in these organizations has contributed to his expertise in developing innovative treatments.

Collaborations

Throughout his career, Imbriglio has collaborated with talented individuals such as Yusheng Xiong and Hyewon Youm. These partnerships have likely enhanced his research and development efforts in the pharmaceutical field.

Conclusion

Jason Eugene Imbriglio is a distinguished inventor whose work in cardiometabolic treatments has the potential to significantly impact healthcare. His innovative patents and collaborations reflect his commitment to advancing medical science and improving patient outcomes.

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