The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2017
Filed:
Aug. 31, 2015
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Jason Imbriglio, Kenilworth, NJ (US);
Clare London, Chatham, NJ (US);
Zhijian LU, Plainfield, IN (US);
James Tata, Kenilworth, NJ (US);
Yusheng Xiong, Kenilworth, NJ (US);
Ming You, Monroe, NJ (US);
Hye Won Youm, Kenilworth, NJ (US);
Jason Imbriglio, Piscataway, NJ (US);
Clare London, Chatham, NJ (US);
Zhijian Lu, Plainfield, IN (US);
James Tata, Westfield, NJ (US);
Yusheng Xiong, Plainsboro, NJ (US);
Ming You, Monroe, NJ (US);
Hyewon Youm, Berkeley Heights, NJ (US);
Merck Sharpe & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention relates to a compound represented by formula I: and pharmaceutically acceptable salts thereof. The compounds of formula I are inhibitors of diacylglyceride O-acyltransferase 2 ('DGAT2') and may be useful in the treatment, prevention and suppression of diseases mediated by DGAT2. The compounds of the present invention may be useful in the treatment of hepatic steatosis, diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, atherosclerosis, cardio-renal diseases such as chronic kidney diseases and heart failure and related diseases and conditions.