The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2025
Filed:
May. 18, 2020
Merck Sharp & Dohme Llc, Rahway, NJ (US);
Changhong Shi, Scotch Plains, NJ (US);
Qingmei Hong, Scotch Plains, NJ (US);
Jason E. Imbriglio, Bridgewater, NJ (US);
Angela D. Kerekes, Plainfield, NJ (US);
Tanweer Khan, Bridgewater, NJ (US);
Claire Lankin, Highbridge, NJ (US);
Derun Li, West Roxbury, MA (US);
Rui Liang, East Brunswick, NJ (US);
Pengcheng Patrick Shao, Fanwood, NJ (US);
Zhicai Wu, Montvale, NJ (US);
Yusheng Xiong, Plainsboro, NJ (US);
Feng Ye, Scotch Plains, NJ (US);
Hyewon Youm, Berkeley Heights, NJ (US);
Yang Yu, Edison, NJ (US);
Anthappan Tony Kurissery, Bangalore, IN;
Venukrishnan Komanduri, Manchester, GB;
Merck Sharp & Dohme LLC, Rahway, NJ (US);
Abstract
The present invention relates to Compounds of Formula I: and pharmaceutically acceptable salts or prodrug thereof. The present invention also relates to compositions comprising at least one compound of Formula I, and methods of using the compounds of Formula I for treatment of cardiometabolic diseases including high blood pressure, heart failure, kidney disease, and diabetes in a subject.