Beijing, China

Hongkui Deng

USPTO Granted Patents = 8 

 

Average Co-Inventor Count = 5.2

ph-index = 2

Forward Citations = 5(Granted Patents)


Company Filing History:


Years Active: 2010-2024

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8 patents (USPTO):

Title: Innovations and Contributions of Hongkui Deng

Introduction

Hongkui Deng is a prominent inventor based in Beijing, China. He has made significant contributions to the field of stem cell research and regenerative medicine. With a total of eight patents to his name, his work focuses on innovative methods for reprogramming cells.

Latest Patents

One of his latest patents is titled "Methods for reprogramming non-pluripotent cells into pluripotent stem cells." This patent provides chemical inducers of pluripotency (CIP), which include glycogen synthase kinase inhibitors, TGFβ receptor inhibitors, cyclic AMP agonists, and S-adenosylhomocysteine hydrolase (SAH) inhibitors or histone acetylators. The method involves contacting a cell with these CIPs for a sufficient period to reprogram the cell into a pluripotent stem cell with embryonic stem cell-like characteristics (CiPSC). Additionally, isolated chemically induced pluripotent stem cells (CiPSCs) and their progeny can be utilized in various applications, including cell therapy and tissue engineering.

Another significant patent is "Methods for chemically induced lineage reprogramming." This patent outlines chemical inducers of lineage reprogramming (CiLR), which also include glycogen synthase kinase inhibitors, TGFβ receptor inhibitors, cyclic AMP agonists, or histone acetylators. The method describes inducing lineage reprogramming in a differentiated cell of one type into a cell with characteristics of a different lineage by contacting the cell with CiLR for a sufficient period.

Career Highlights

Hongkui Deng has worked at notable institutions, including Peking University and Hong Guan Ltd. His research has significantly advanced the understanding of cell reprogramming and its potential applications in medicine.

Collaborations

He has collaborated with esteemed colleagues such as Yan Shi and Yang Zhao, contributing to the advancement of innovative research in his field.

Conclusion

Hongkui Deng's work in cell reprogramming and stem cell research has paved the way for new therapeutic approaches in regenerative medicine. His patents reflect a commitment to innovation and the potential for significant impact in the medical field.

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