The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 11, 2021
Filed:
Aug. 04, 2015
Peking University, Beijing, CN;
Peking University Shenzhen Graduate School, Guangdong, CN;
Beijing Ruipu Chenchuang Technology Co., Ltd., Beijing, CN;
Hongkui Deng, Beijing, CN;
Haisong Liu, Beijing, CN;
Dicong Zhu, Beijing, CN;
Huan Yang, Beijing, CN;
Zhen Liang, Beijing, CN;
PEKING UNIVERSITY, Beijing, CN;
PEKING UNIVERSITY SHENZHEN GRADUATE SCHOOL, Guangdong, CN;
BEIJING RUIPU CHENCHUANG TECHNOLOGY CO., LTD., Beijing, CN;
Abstract
SUSD2 protein is used as a marker in identification, selection or separation of pancreatic internal secretion precursor cells and/or newborn pancreatic internal secretion cells; and a use of an mRNA, for encoding the SUSD2 protein, of a precursor protein as the marker in identification of the pancreatic internal secretion precursor cells and/or the newborn pancreatic internal secretion cells. Analysis of gene expression of pancreatic endoderm cells sourced by induced directional differentiation of human pluripotent stem cells finds the enrichment expression of a SUSD2 gene in the pancreatic internal secretion precursor cells and the newborn pancreatic internal secretion cells. A protein encoded by the SUSD2 gene is a receptor protein on cell membranes. Using the protein as the marker, the identification, the selection or the separation of the pancreatic internal secretion precursor cells and the newborn pancreatic internal secretion cells can be conducted.