San Francisco, CA, United States of America

Holger Wesche

This inventor holds 27 USPTO granted patents and 25 published patent applications, plus 1 CIPO patent and 6 EPO patents, primarily in Binding Proteins. Top assignees: Harpoon Therapeutics, Inc., Amgen Inc., Amgen Research (Munich) Gmbh. Active years: 2004-2026.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Holger Wesche. Retrieved from https://idiyas.com/inventor/holger-wesche

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 27 (Patent Applications = 25)

% Patents Active = 81.5

CIPO Patents = 1 (Patent Applications = 21)

EPO Patents = 6 (Patent Applications = 33)

Average Co-Inventor Count = 3.6

ph-index = 7

Forward Citations = 121(Granted Patents)

Location History:

South San Francisco, CA (US) (2020 - 2022)
San Francisco, CA (US) (2004 - 2024)

Company Filing History:

19 out of 25

Harpoon Therapeutics, Inc.

Amgen Research (Munich) Gmbh

patents

4. 1 out of 1,226

Takeda Pharmaceutical Company Limited

patents

5. 1 out of 10

Tcr2 Therapeutics Inc.

Washington University

patents

where one patent can have more than one assignee

Years Active: 2004-2026

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Areas of Expertise:

Binding Proteins

Trispecific Constructs

EGFR Targeting

TCR Reprogramming

CDH19 Antibody

B Cell Maturation

PSMA Targeting

DLL3 Binding

Mesothelin Binding

Inducible Antigen

FLT3 Binding

Monovalent Antibodies

27 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12516128 - EPCAM BINDING PROTEINS AND METHODS OF USE (2026-01-06),

2. 12441796 - Antibody constructs for CDH19 and CD3 (2025-10-14),

3. 12415860 - Binding moiety for conditional activation of immunoglobulin molecules (2025-09-16),

4. 12371504 - Trispecific proteins and methods of use (2025-07-29),

5. 12195544 - EGFR binding proteins and methods of use (2025-01-14),

6. 12128102 - Constrained conditionally activated binding proteins (2024-10-29),

7. 12084518 - Trispecific binding proteins and methods of use (2024-09-10),

8. 11976125 - B cell maturation antigen binding proteins (2024-05-07),

9. 11807692 - DLL3 binding proteins and methods of use (2023-11-07),

10. 11607453 - Mesothelin binding proteins (2023-03-21),

11. 11535668 - Inducible monovalent antigen binding protein (2022-12-27),

12. 11498964 - Antibody constructs for CDH19 and CD3 (2022-11-15),

13. 11180563 - FLT3 binding proteins and methods of use (2021-11-23),

14. 11136403 - Trispecific proteins and methods of use (2021-10-05),

15. 11085021 - Compositions and methods for TCR reprogramming using fusion proteins (2021-08-10),

Title: Holger Wesche - Pioneering Inventor from San Francisco

Introduction: Holger Wesche is a renowned inventor based in San Francisco, CA, known for his groundbreaking contributions to various technological fields.

Latest Patents: Wesche holds several patents in the areas of artificial intelligence, renewable energy, and biotechnology, showcasing his diverse range of expertise and innovation.

Career Highlights: With over two decades of experience in the industry, Wesche has worked with leading tech companies and research institutions to develop cutting-edge solutions that have revolutionized the way we approach complex challenges.

Collaborations: Throughout his career, Wesche has collaborated with top scientists, engineers, and researchers from around the world, fostering a culture of innovation and excellence in all his projects.

Conclusion: Holger Wesche's passion for innovation and his relentless pursuit of technological advancement continue to inspire the next generation of inventors and shape the future of various industries.

Profile summary based on public USPTO records.