The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 10, 2021

Filed:

Aug. 10, 2020
Applicant:

Tcr2 Therapeutics Inc., Cambridge, MA (US);

Inventors:

Patrick Baeuerle, Gauting, DE;

Gregory Sieczkiewicz, Cambridge, MA (US);

Robert Hofmeister, Scituate, MA (US);

Holger Wesche, San Francisco, CA (US);

Bryan D. Lemon, Mountain View, CA (US);

Richard J. Austin, San Francisco, CA (US);

Robert B. Dubridge, Belmont, CA (US);

Assignee:

TCR2 THERAPEUTICS INC., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C12N 5/0783 (2010.01); A61P 35/00 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0638 (2013.01); A61P 35/00 (2018.01); C07K 14/4748 (2013.01); C07K 16/18 (2013.01); C07K 16/28 (2013.01); C12N 5/0646 (2013.01); A61K 2039/505 (2013.01); A61K 2039/572 (2013.01); A61K 2039/585 (2013.01); A61K 2039/6006 (2013.01); C07K 2317/70 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01); C07K 2319/70 (2013.01);
Abstract

Provided herein are T-cell receptor (TCR) fusion proteins (TFPs), T-cells engineered to express one or more TFPs, and methods of use thereof for the treatment of diseases, including cancer.


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