Basel, Switzerland

Georg Jaeschke

This inventor holds 86 USPTO granted patents and 36 published patent applications, plus 10 CIPO patents and 54 EPO patents, primarily in Cancer Therapeutics (CPC class C07D487-04). Top assignees: Hoffmann-La Roche Inc., C4 Therapeutics, Inc., Roche Palo Alto LLC. Active years: 2001-2026.

USPTO Granted Patents = 86 

% Patents Active = 64.0

 

 

Average Co-Inventor Count = 5.9

ph-index = 7

Forward Citations = 229(Granted Patents)

Forward Citations (Not Self Cited) = 126(Dec 10, 2025)


Inventors with similar research interests:


Location History:

  • Basle, CH (2001)
  • Basel, CH (2001 - 2024)

Company Filing History:


Years Active: 2001-2026

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Areas of Expertise:
EGFR Inhibitors
Indazole Derivatives
Isoindolinone Compounds
Ethynyl Derivatives
Cancer Treatment
Allosteric Inhibitors
CNS Disorders
Bridged Piperidine
Arylsulfonamide
Metabotropic Glutamate Receptor
Substituted Imidazoles
Ethynyl Compounds
86 patents (USPTO):Explore Patents

Title: The Innovative Journey of Georg Jaeschke: A Pioneer in Pharmaceutical Patents

Introduction: Georg Jaeschke, based in Basel, Switzerland, is a prominent inventor recognized for his significant contributions to the field of pharmaceuticals. With an impressive portfolio of 78 patents, he has made notable advancements, particularly in the development of compounds aimed at targeting specific cancers and other health conditions.

Latest Patents: Among his latest innovations are two remarkable patents. The first patent focuses on isoindolinone derivatives as selective allosteric inhibitors of EGFR mutant cancers. This invention details compounds that specifically target and inhibit T790M/L858R, T790M/L858R/C797S, L858R, and L858R/C797S containing EGFR mutants. It further includes their manufacturing process, pharmaceutical compositions, and therapeutic applications.

The second patent pertains to ethynyl derivatives that act as metabotropic glutamate receptor antagonists. These compounds are designed for therapeutic use in treating various conditions, such as anxiety, pain, depression, Fragile-X syndrome, autism spectrum disorders, Parkinson's disease, and gastroesophageal reflux disease (GERD).

Career Highlights: Georg Jaeschke has enjoyed a prolific career in the pharmaceutical industry. He has worked with renowned organizations, including Hoffmann-La Roche Inc. and Roche Palo Alto LLC. His experience in these leading companies has allowed him to pioneer research and development in innovative therapeutic compounds.

Collaborations: Throughout his career, Georg has collaborated with esteemed colleagues such as Eric Vieira and Daniel Rueher. Their combined expertise has fostered an environment of creativity and innovation, further propelling advancements in pharmaceutical research.

Conclusion: Georg Jaeschke's work exemplifies the spirit of innovation and the continuous quest for advancements that address medical challenges. His extensive patent portfolio highlights his contribution to developing targeted therapies, marking him as a significant figure in the realm of pharmaceutical inventions. Through his dedication and collaboration with industry professionals, Georg continues to influence the future of healthcare innovation in meaningful ways.

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