The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 11, 2024
Filed:
May. 09, 2021
Applicant:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventors:
Barbara Biemans, Riehen, CH;
Wolfgang Guba, Muellheim, DE;
Georg Jaeschke, Basel, CH;
Lothar Lindemann, Basel, CH;
Fionn O'Hara, Basel, CH;
Antonio Ricci, Biel-Benken, CH;
Daniel Rueher, Raedersdorf, FR;
Eric Vieira, Frenkendorf, CH;
Assignee:
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/527 (2006.01); A61P 1/08 (2006.01); A61P 3/10 (2006.01); A61P 25/00 (2006.01); A61P 25/16 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01); A61P 35/00 (2006.01); C07D 401/10 (2006.01); C07D 471/10 (2006.01); C07D 487/10 (2006.01); C07D 491/107 (2006.01); C07D 491/20 (2006.01);
U.S. Cl.
CPC ...
C07D 487/10 (2013.01); A61P 1/08 (2018.01); A61P 3/10 (2018.01); A61P 25/00 (2018.01); A61P 25/16 (2018.01); A61P 25/22 (2018.01); A61P 25/24 (2018.01); A61P 35/00 (2018.01); C07D 401/10 (2013.01); C07D 471/10 (2013.01); C07D 491/107 (2013.01); C07D 491/20 (2013.01);
Abstract
The present invention relates to positive allosteric modulators (PAMs) of metabotropic glutamate receptor 4 (mGluR4) that may be used for the treatment of conditions such as Parkinson's disease, anxiety, emesis, obsessive compulsive disorder, autism, neuroprotection, cancer, depression and diabetes type 2.