David G Gorenstein

USPTO Granted Patents = 10 (Patent Applications = 2)

CIPO Patents = 1 (Patent Applications = 6)

EPO Patents = 1

Average Co-Inventor Count = 3.5

ph-index = 5

Forward Citations = 227(Granted Patents)

Location History:

Carmel, IN (US) (1993)
Houston, TX (US) (2002 - 2018)

Company Filing History:

8 out of 5,445

University of Texas System

patents

1 out of 1

Mei Technologies, Inc.

patent

1 out of 1

Bd. of Regents, Univ. of Texas

patent

4. 1 out of 2,657

Purdue Research Foundation

patents

5. 1 out of 2

Am Biotechnologies, Inc.

patents

where one patent can have more than one assignee

Years Active: 1993-2018

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10 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 9988623 - Methods of X-aptamer generation and compositions thereof (2018-06-05),

2. 9567579 - Structure based and combinatorially selected oligonucleoside phosphorothioate and phosphorodithioate aptamer targeting AP-1 transcription factors (2017-02-14),

3. 8658614 - Aptamer-containing compositions and methods for targeting E-selectin (2014-02-25),

4. 7910523 - Structure based and combinatorially selected oligonucleoside phosphorothioate and phosphorodithioate aptamer targeting AP-1 transcription factors (2011-03-22),

5. 7576037 - Process and apparatus for combinatorial synthesis (2009-08-18),

6. 7338762 - Bead bound combinatorial oligonucleoside phosphorothioate and phosphorodithioate aptamer libraries (2008-03-04),

7. 7179894 - Combinatorial selection of oligonucleotide aptamers (2007-02-20),

8. 6867289 - Thio-modified aptamer synthetic methods and compositions (2005-03-15),

9. 6423493 - Combinatorial selection of oligonucleotide aptamers (2002-07-23),

10. 5218088 - Process for preparing dithiophosphate oligonucleotide analogs via (1993-06-08),

Title: David G Gorenstein: Innovator in Aptamer Technology

Introduction

David G Gorenstein is a prominent inventor based in Houston, TX (US), known for his significant contributions to the field of aptamer technology. With a total of 10 patents, Gorenstein has made remarkable advancements that have implications in various scientific and medical applications.

Latest Patents

Among his latest patents, Gorenstein has developed methods for X-aptamer generation and compositions thereof. This innovative approach introduces a novel bead-based next-generation 'X-aptamer' selection scheme that extends aptamer technology to include X-modified bases. The result is the creation of X-aptamers, which can be synthesized via a split-pool scheme on individual beads. This technology allows for chemical modifications to be introduced at any position along the aptamer sequence, including the phosphate backbones, and can be applied to various DNA modifications. Another significant patent involves structure-based and combinatorially selected oligonucleoside phosphorothioate and phosphorodithioate aptamers targeting AP-1 transcription factors. This invention includes methods for creating a combinatorial library to identify modified thioaptamers that can bind to and influence the immune response of host animals.

Career Highlights

Gorenstein has worked with notable organizations, including the University of Texas System and Mei Technologies, Inc. His work has been instrumental in advancing the understanding and application of aptamer technology in therapeutic contexts.

Collaborations

Throughout his career, Gorenstein has collaborated with esteemed colleagues such as Bruce A Luxon and Johnnie Engelhardt. These partnerships have contributed to the development of innovative solutions in the field of molecular biology.

Conclusion

David G Gorenstein's contributions to aptamer technology exemplify the impact of innovative thinking in scientific research. His patents and collaborations continue to influence advancements in medical and biotechnological applications.

This text is generated by artificial intelligence and may not be accurate.