The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 25, 2014
Filed:
Aug. 15, 2011
David G. Gorenstein, Houston, TX (US);
Takemi Tanaka, Philadelphia, PA (US);
Anoma Somasunderam, Galveston, TX (US);
Aman Mann, Houston, TX (US);
David G. Gorenstein, Houston, TX (US);
Takemi Tanaka, Philadelphia, PA (US);
Anoma Somasunderam, Galveston, TX (US);
Aman Mann, Houston, TX (US);
The University of Texas Health Science Center, Houston, TX (US);
Abstract
An isolated nucleic acid molecule that selectively binds to an E-selectin protein comprises a contiguous 29-30 nucleotide sequence that includes at least one monothiophosphate or a dithiophosphate modified nucleotide. Also disclosed are methods of inhibiting an E-selectin mediated interaction with a natural E-selectin ligand, and methods of targeting an imaging agent or therapeutic agent to a target tissue bearing E-selectin.