The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 15, 2005
Filed:
Oct. 25, 1999
David G. Gorenstein, Houston, TX (US);
Bruce A. Luxon, Galveston, TX (US);
Norbert Herzog, Friendswood, TX (US);
Judy Aronson, Galveston, TX (US);
David G. Gorenstein, Houston, TX (US);
Bruce A. Luxon, Galveston, TX (US);
Norbert Herzog, Friendswood, TX (US);
Judy Aronson, Galveston, TX (US);
Board of Regents, The University of Texas Systems, Austin, TX (US);
Abstract
This invention generally relates the generation of aptamers and to the use of aptamers as diagnostic and therapeutic agents. More particularly, the present invention relates to methods using combinatorial chemistry to prepare aptamers having controlled thiophosphate replacement in the phosphate backbone for improved binding efficiencies to a target and to RNA and/or DNA products having novel nucleotide sequences and enhanced target binding efficacies.