Norbert Herzog

Title: Norbert Herzog: Innovator in Oligonucleoside Technologies

Introduction

Norbert Herzog is a distinguished inventor based in Friendswood, TX (US). He has made significant contributions to the field of oligonucleoside technologies, holding a total of 2 patents. His work focuses on the development of innovative methods and compositions that enhance the efficacy of nucleic acid aptamers.

Latest Patents

Herzog's latest patents include "Bead bound combinatorial oligonucleoside phosphorothioate and phosphorodithioate aptamer libraries." This invention encompasses compositions and methods for creating a combinatorial library featuring multiple beads, each attached to a unique nucleic acid aptamer with a distinct sequence. The aptamers may be covalently linked to polystyrene beads and can include various linkages such as phosphorothioate and phosphorodithioate. Additionally, Herzog's patent titled "Thio-modified aptamer synthetic methods and compositions" relates to the generation of aptamers for diagnostic and therapeutic applications. This invention utilizes combinatorial chemistry to produce aptamers with controlled thiophosphate replacements, improving their binding efficiencies to target molecules.

Career Highlights

Norbert Herzog is affiliated with the University of Texas System, where he continues to advance research in the field of oligonucleotides. His innovative approaches have garnered attention and recognition within the scientific community.

Collaborations

Herzog has collaborated with notable colleagues, including David G. Gorenstein and Bruce A. Luxon, contributing to the advancement of research in aptamer technologies.

Conclusion

Norbert Herzog's contributions to oligonucleoside technologies through his patents and collaborations highlight his role as a key innovator in the field. His work continues to pave the way for advancements in diagnostic and therapeutic applications.