The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 04, 2008

Filed:

Apr. 21, 2004
Applicants:

David G. Gorenstein, Houston, TX (US);

Xianbin Yang, Webster, TX (US);

Bruce A. Luxon, Galveston, TX (US);

Norbert Herzog, Friendswood, TX (US);

Inventors:

David G. Gorenstein, Houston, TX (US);

Xianbin Yang, Webster, TX (US);

Bruce A. Luxon, Galveston, TX (US);

Norbert Herzog, Friendswood, TX (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C07K 7/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention includes composition and methods for making and using a combinatorial library having two or more beads, wherein attached to each bead is a unique nucleic acid aptamer that have disposed thereon a unique sequence. The library aptamers may be attached covalently to the one or more beads, which may be polystyrene beads. The aptamers may include phosphorothioate, phosphorodithioate and/or methylphosphonate linkages and may be single or double stranded DNA, RNA or even PNAs.


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