Location History:
- La Jolla, CA (US) (2020)
- San Diego, CA (US) (2015 - 2023)
Company Filing History:
Years Active: 2015-2025
Title: **Clodagh O'Shea: Innovating Cancer Treatment through Advanced Adenovirus Research**
Introduction
Clodagh O'Shea is a notable inventor based in San Diego, CA, recognized for her groundbreaking contributions to the field of virology and cancer treatment. With a remarkable portfolio of 14 patents, she has focused her research on developing innovative recombinant adenoviruses aimed at enhancing therapeutic applications for cancer patients.
Latest Patents
O'Shea's latest patents reflect her commitment to advancing medical science. One of her significant inventions is the "Oncolytic adenovirus with enhanced replication properties comprising modifications in E1A, E3, and E4." This patent describes tumor-selective recombinant adenoviruses designed to enhance replication while reducing unintended effects on non-tumor cells. Specifically, her development involves the manipulation of adenovirus genes to improve selective replication in tumor cells and minimize targeting effects on the liver, showcasing her dedication to targeted cancer therapies.
Another important patent by O'Shea discusses "Exogenous gene expression in recombinant adenovirus for minimal impact on viral kinetics." This work involves the innovative integration of exogenous open reading frames (ORFs) and self-cleaving peptide coding sequences into recombinant adenoviruses. Her research emphasizes the optimal placement of these genes to ensure that there is minimal disruption to viral kinetics, further broadening the therapeutic potential of these recombinant viruses.
Career Highlights
Clodagh O'Shea has built her career at the Salk Institute for Biological Studies, a prestigious research institution known for its outstanding contributions to biological research. Her role at the institute has allowed her to focus on groundbreaking research that not only pushes the boundaries of virology but also provides healthier outcomes for cancer patients through innovative therapies.
Collaborations
Throughout her career, O'Shea has collaborated with notable colleagues, including Colin Powers and William N Partlo. These collaborations have been instrumental in fostering an environment of innovation and cross-disciplinary research that enhances the effectiveness of her patented technologies.
Conclusion
Clodagh O'Shea stands out as a pioneering inventor in the realm of cancer research, with her 14 patents reflecting her commitment to developing advanced solutions through recombinant adenoviruses. Her work at the Salk Institute for Biological Studies and collaboration with esteemed colleagues exemplify her dedication to improving cancer treatment methodologies and contributing to the future of medical science.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.